Tuesday, January 13, 2015

Odontogenic Tumor : Defination & Classification


Definition: Odontogenic Tumors or neoplasms are a complex group of lesions derived from the dental formative tissues or their remnants ( tissues associated with the development of tooth and its supporting structures ). The constituent tissues in each of these neoplasms can resemble the various tissues found during normal odantogenesis,from inception of the tooth germ to tooth eruption.

The tooth formation or odontogenesis begins in the 6th week intra-uterin life and it originates from the oral epithelium covering the maxillary and mandibular alveolar processes .During the initial period “bud-like” swellings appear from the basal layer of the oral epithelium at specific location where individual teeth will appear from in future .


Benign Odontogenic Neoplasms 

Ameloblastoma a kind of odontogenic tumor in left jaw:

Case courtesy of Dr Frank Gaillard, Radiopaedia.org

1.  Neoplasms of epithelial tissue origin 

a. Ameloblastoma

b. Squamous odontogenic tumor

c. Calciflying epithelial odontogenic tumor (CEOT)

d. Clear cell odontogenic tumor.

2.  Neoplasms of mixed tissue origin (Made up of both epithelium and mesenchymal tissues)

a. Adenomatoid odontogenic tumor (AOT)

b. Ameloblastic fibroma

c. Ameloblastic fibro-odontoma / fibroden-tinoma

d. Odonto-ameloblastoma

e. Complex odontoma

f. Compound odontoma

g. Calcifying epithelial odontogenic cyst.

3.  Neoplasms of the mesenchymal tissue origin 

a. Odontogenic fibroma

b. Odontogenic myxoma

c. Cementoma

d. Famillial gigantiform cementoma

e. Cementifyin fibroma

f. Bening cementolastoma

Malignant Tumors

1.  Odontogenic carcinomas :

a. Malignant ameloblastoma

b. Primary intra-alveolar carcinoma

c. Malignant variants of other epithelial tissue neoplasms

d. Malignant changes in odontogenic cysts.

2.  Odontogenic sarcomas :

a. Ameloblastic fibrosarcoma

b. Ameloblastic carcinosarcoma

c. Ameloblastic fibrodentinosarcoma

Neoplasms of Debatable Origin 

• Melanotic neuro-ectodermal tumor of infancy 

• Congenital gingival granular cell tumor (congenital epulis)


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